Friday, June 22, 2007

Prof. Orest Blaschuk's Prolific Patents in Cadherin Cell Adhesion Science

Prof Orest Blachuk of McGill University Dept. of Urology has racked up an impressive portfolio of patents and patent applications. He is cofounder of Adherex Technology and its scientific luminary. Adherex is on the path to some significant advances in cancer treatment prognoses.

US7138369 Compounds and methods for modulating apoptosis
US7122623 Compounds and methods for modulating cell adhesion
US20060183884 Compounds and methods for modulating cell adhesion
US7063842 Compounds and methods for inhibiting the interaction between .alpha.-catenin and .beta.-catenin
US6967238 Compounds and methods for modulating cell adhesion
US6962969 Compounds and methods for modulating nonclassical cadherin-mediated functions
US20050222037 Compounds and methods for modulating VE-cadherin-mediated function
US20050215482 Compounds and methods for modulating OB-cadherin-mediated function
US20050203025 Compounds and methods for modulating nonclassical cadherin-mediated functions
US-APP20050163786 Compounds and methods for modulating adhesion molecule function
US6914044 Compounds and methods for modulating cell adhesion
US20050129676 Compounds and methods for modulating functions of classical cadherins
US20050037973 Compounds and methods for cancer therapy
US20040254099 Compounds and methods for modulating beta-catenin mediated gene expression
US6830894 Compounds and methods for modulating claudin-mediated functions
US20040248219 Methods for diagnosing and evaluating cancer
US20040248220 Methods for diagnosing and evaluating cancer
US20040229811 Compounds and methods for modulating desmosomal cadherin-mediated functions
US6806255 Compounds and methods for modulating adhesion molecule function
US6797807 Compounds and methods for cancer therapy
US20040175361 Compounds and methods for modulating functions of nonclassical cadherins
US6780845 Compounds and methods for cancer therapy
US20040142854 Compounds and methods for stimulating beta-catenin mediated gene expression and differentiation
US20040132651 Compounds and methods for regulating cell adhesion
US6756356 Compounds and methods for modulating claudin-mediated functions
US20040106545 Compounds and methods for modulating cell adhesion
US6723700 Compounds and methods for modulating claudin-mediated functions
US20040058864 Peptidomimetic modulators of cell adhesion
US6706685 Compounds and methods for stimulating .beta.-catenin mediated gene expression and differentiation
US6682901 Methods for diagnosing and evaluating cancer
US6683048 Compounds and methods for stimulating gene expression and cellular differentiation
US6680175 Methods for diagnosing and evaluating cancer
US6677116 Methods for treating cancer by modulating .beta.-catenin mediated gene expression
US20040006011 Peptidomimetic modulators of cell adhesion
US20030236186 Compounds and methods for inhibiting the interaction between alpha-catenin and beta-catenin
US20030229199 Compounds and methods for modulating nonclassical cadherin-mediated functions
US20030224978 Compounds and methods for modulating apoptosis
US6638911 Compounds and methods for modulating desmosomal cadherin-mediated functions
US6610821 Compounds and methods for modulating endothelial cell adhesion
US6593297 Compounds and methods for inhibiting cancer metastasis
US20030109454 Compounds and methods for modulating adhesion molecule function
US6569996 Antibody that specifically binds to the cadherin-5 cell adhesion recognition sequence
US20030096746 Compounds and methods for inhibiting cancer metastasis
US6562786 Compounds and methods for modulating apoptosis
US20030087811 Compounds and methods for cancer therapy
US20030082166 Compounds and methods for modulating nonclassical cadherin-mediated functions
US6551994 Compounds and methods for inhibiting the interaction between .alpha.-catenin and .beta.-catenin
US20030065136 Compounds and methods for modulating cell adhesion
US20030027761 Compounds and methods for modulating junctional adhesion molecule-mediated functions
US20030013655 Compounds and methods for regulating cell adhesion

US20020193294 COMPOUNDS AND METHODS FOR MODULATING CLAUDIN-MEDIATED FUNCTIONS
US20020168761 Peptidomimetic modulators of cell adhesion
US20020169106 COMPOUNDS AND METHODS FOR INHIBITING CANCER METASTASIS
US6472368 Compounds and methods for modulating adhesion molecule function
US6472367 Compounds and methods for modulating OB-cadherin mediated cell adhesion
US20020151475 Compounds and methods for modulating cell adhesion
US6465427 Compounds and methods for modulating cell adhesion
US20020146687 METHODS FOR DIAGNOSING AND EVALUATING CANCER
US20020123044 METHODS FOR DIAGNOSING AND EVALUATING CANCER
US6433149 Compounds and methods for inhibiting cancer metastasis
US6417325 Compounds and methods for cancer therapy
US6391855 Compounds and methods for modulating junctional adhesion molecule-mediated functions
US6358920 Compounds and methods for modulating nonclassical cadherin-mediated functions
US6346512 Compounds and methods for modulating cell adhesion
US6333307 Compounds and method for modulating neurite outgrowth
US6326352 Compounds and methods for modulating cell adhesion
US6310177 Compounds and methods for modulating tissue permeability
US6303576 Compounds and methods for modulating .beta.-catenin mediated gene expression
US6277824 Compounds and methods for modulating adhesion molecule function
US6248864 Compounds and methods and modulating tissue permeability
US6207639 Compounds and methods for modulating neurite outgrowth
US6203788 Compounds and methods for regulating cell adhesion
US6169071 Compounds and methods for modulating cell adhesion
US6110747 Compounds and methods for modulating tissue permeability
US6031072 Compounds and methods for modulating cell adhesion

What a heck of a substantive patent portfolio.

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